Reversible Segmental Cerebral Arterial Vasospasm and Cerebral Infarction

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Reversible segmental cerebral arterial vasospasm and cerebral infarction: possible association with excessive use of sumatriptan and Midrin.

OBJECTIVE To describe a patient who developed reversible segmental cerebral arterial vasospasm and cerebral infarction while taking excessive amounts of sumatriptan succinate and a combination drug (Midrin) consisting of isometheptene mucate, 65 mg, dichloralphenazone, 100 mg, and acetaminophen, 325 mg. DESIGN Case report. SETTING Tertiary care center. PATIENT A 43-year-old man who develo...

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Vasoconstriction is not recognized as a cause of cerebrovascular disease except in the vasospasm seen following subarachnoid hemorrhage and possibly in migraine. However, we found four patients to have transient, fully reversible vasoconstriction and dilatation prominently involving arteries around the circle of Willis. All four patients were evaluated for severe headaches and fluctuating or re...

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ژورنال

عنوان ژورنال: Archives of Neurology

سال: 1998

ISSN: 0003-9942

DOI: 10.1001/archneur.55.5.712